We are interested in several topics related to cyanobacterial biology, from their occurrence in natural habitats, their molecular biology and biochemical properties, to biotechnology applications.

A special interest is devoted to toxin-antitoxin systems and cell death related enzymes. In the past few years we collected substantial experience in cyanobacterial synthetic biology as well.

Check links below for details about our research.

• Ecology Cell Death Enzymes Toxins/Antitoxins Biotech Toolbox Synthetic Biology Biosafety Other Algae

Publications List

2018
 KLEMENČIČ, Marina, FUNK, Christiane. Type III metacaspases: calcium-dependent activity proposes new function for the p10 domain. New Phytologist 218(3), 1179-1191.

KLEMENČIČ, Marina, FUNK, Christiane. Structural and functional diversity of caspase homologues in non-metazoan organisms. Protoplasma 255(1), 387-397.

2017

 JUTERŠEK, Mojca, KLEMENČIČ, Marina, DOLINAR, Marko. Discrimination between Synechocystis members (cyanobacteria) based on heterogeneity of their 16S rRNA and ITS regions. Acta Chimica Slovenica 64(4), 804-817.

KLEMENČIČ, Marina, NIELSEN, A.Z., SAKURAGI, Y., FRIGAARD, N.-U., ČELEŠNIK, Helena Sabina, JENSEN, P.E., DOLINAR, Marko. Synthetic biology of cyanobacteria for production of biofuels and high-value products. In: GONZALEZ-FERNANDEZ, Cristina &  MUÑOZ, Raul (Eds.). Microalgae-based biofuels and bioproducts : from feedstock cultivation to end-products, (Woodhead Publishing Series in Energy). Kidlington: Woodhead Publishing. pp. 305-325.

2016
 KLEMENČIČ, Marina, DOLINAR, Marko (2016) Orthocaspase and toxin-antitoxin loci rubbing shoulders in the genome of Microcystis aeruginosa PCC 7806. Current Genetics 62(4), 669-675.

ČELEŠNIK, Helena, TANŠEK. Anja, TAHIROVIĆ, Aneja, VIŽINTIN, Angelika, MUSTAR, Jernej, VIDMAR, Vita, DOLINAR, Marko (2016) Biosafety of biotechnologically important microalgae: intrinsic suicide switch implementation in cyanobacterium Synechocystis sp. PCC 6803. Biology Open 5, 519-528.

KLEMENČIČ, Marina, OSOJNIK ČRNIVEC, Ilja Gasan, PINTAR, Albin, DOLINAR, Marko (2016) Synthetic biology for biobutanol production. (Text in Slovenian) Acta Chimica Slovenica 63(1) S3-S9.

2015
KLEMENČIČ, Marina, NOVINEC, Marko, DOLINAR, Marko (2015) Orthocaspases are proteolytically active prokaryotic caspase homologues: the case of Microcystis aeruginosa. Molecular Microbiology 98(1), 142-150.

2014
ŠKRLJ, Nives, DOLINAR, Marko (2014) New engineered antibodies against prions. Bioengineered 5(1), 1-5.

2013
ŠKRLJ, Nives, DREVENŠEK, Gorazd, HUDOKLIN, Samo, ROMIH, Rok, ČURIN-ŠERBEC, Vladka, DOLINAR, Marko (2013) Recombinant single-chain antibody with the trojan peptide penetratin positioned in the linker region enables cargo transfer across the blood-brain barrier. Applied Biochemistry and Biotechnology 169(1), 159-169

2011
ŠKRLJ, Nives, VRANAC, Tanja, POPOVIĆ, Mara, ČURIN-ŠERBEC, Vladka, DOLINAR, Marko (2011) Specific binding of the pathogenic prion isoform: development and characterization of a humanized single-chain variable antibody fragment. PLoS One 6(1), e15783

2010
ŠKRLJ, Nives, VIDRIH, Zlatko, DOLINAR, Marko (2010) A universal approach for promoter strength evaluation supported by the web-based tool PromCal. Analytical Biochemistry 396(1), 83-90

ŠKRLJ, Nives, ČURIN-ŠERBEC, Vladka, DOLINAR, Marko (2010) Single-chain Fv antibody fragments retain binding properties of the monoclonal antibody raised against peptide P1 of the human prion protein. Applied Biochemistry and Biotechnology 160(6), 1808-1821.